Forensic Chemistry > 3. Because proteins are a major structural and metabolic component of all living organisms, the analysis of protein samples can be useful in forensic chemistry > The Different Uses of Proteins >
Distinguish between protein used for structural purposes and the uses of proteins as enzymes
Proteins
- is known as the most abundant biomolecule having its building blocks called amino acids
- can be classified in terms of its shape, function and composition.
Based on Shape:
- Globular (spherical) – Generally soluble in water
Example: Hemoglobin - Fibrous (thread-like) – Stretched, twisted and generally insoluble in water
- Globular (spherical) – Generally soluble in water
Example: Collagen
Based on Composition:
- Simple – pure protein
Example: Globulin, Albumin - Conjugated – protein with non-protein substances
Example: Glycoproteins, Lipoproteins
Based on Biological Function:
a. Transport Proteins
b. Nutrient and Storage Proteins
c. Contractile Proteins
d. Defense Proteins
e. Regulatory Proteins
f. Enzymes
– serve as catalyst of biological reactions
– generally globular and water soluble
-contain active site where catalysis occurs
– all enzymes are proteins except for ribozymes
– can be classified as oxidoreductases, transferases, hydrolases, lyases, isomerases and ligases
Examples: Insulin , Hemoglobin, Lipase, Pepsin, Hexokinase, Pyruvate decarboxylase
g. Structural Proteins
– stingy, physically tough and insoluble in water which work for structural support
Example: Keratin in skin, fingernails and hair